Does Trelegy (fluticasone furoate, umeclidinium, vilanterol) cause a bad taste?

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Last updated: May 2, 2025View editorial policy

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From the Guidelines

Trelegy can cause a bad taste in the mouth, but this side effect can be managed by rinsing your mouth thoroughly with water after each use and implementing good oral hygiene practices. To minimize the unpleasant taste, it is recommended to brush your teeth after using Trelegy and stay hydrated throughout the day 1. Additionally, using sugar-free mints or gum between doses may temporarily mask the taste. The bad taste is a common side effect of Trelegy, which contains fluticasone and other ingredients that can linger in the mouth if not properly rinsed away. Some key points to consider when managing the bad taste caused by Trelegy include:

  • Rinsing your mouth with water after each use
  • Brushing your teeth after using Trelegy
  • Staying hydrated throughout the day
  • Using sugar-free mints or gum between doses It is essential to note that while the bad taste can be bothersome, it is typically not dangerous, and the benefits of controlling your respiratory condition with Trelegy usually outweigh this side effect 1. If the taste is severe or persistent despite these measures, it is crucial to consult your healthcare provider, as they might suggest adjusting your inhalation technique or consider alternative medications. Never stop taking Trelegy without medical advice, as this can have negative consequences on your respiratory health.

From the Research

Trelegy Bad Taste

  • There is no direct information available in the provided studies regarding the bad taste of Trelegy.
  • The studies primarily focus on the efficacy and safety of Trelegy (fluticasone furoate/umeclidinium/vilanterol) in patients with chronic obstructive pulmonary disease (COPD) 2, 3, 4, 5, 6.
  • None of the studies mention taste as a side effect or a characteristic of Trelegy.
  • It is possible that the dry powder inhaler formulation of Trelegy may not have a significant taste, but this is not explicitly stated in the available evidence.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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