What is the differential diagnosis for a 13-year-old patient presenting with cough and soreness on the tongue?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 2, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for 13-year-old with Cough and Sore on Tongue

  • Single most likely diagnosis:
    • Viral pharyngitis: This is the most common cause of a sore tongue and cough in a 13-year-old, often accompanied by other symptoms like fever and sore throat.
  • Other Likely diagnoses:
    • Bacterial pharyngitis (Strep throat): Although less common than viral pharyngitis, it's a significant consideration due to the potential for complications if left untreated.
    • Allergic rhinitis: Postnasal drip from allergies can cause cough and irritation to the tongue and throat.
    • Acid reflux (Gastroesophageal reflux disease, GERD): Stomach acid flowing up into the throat can cause irritation and soreness, potentially leading to cough.
  • Do Not Miss diagnoses:
    • Infectious mononucleosis: Although less common, it can present with sore throat and could be accompanied by a cough, with the additional risk of splenomegaly and other complications.
    • Pertussis (Whooping cough): Given the cough symptom, pertussis is a critical diagnosis not to miss, especially in areas with low vaccination rates or outbreaks.
    • Oral thrush: Especially if the patient is immunocompromised, oral thrush can cause a sore tongue and should be considered to ensure appropriate antifungal treatment.
  • Rare diagnoses:
    • Autoimmune disorders (e.g., pemphigus, lupus): These can cause oral ulcers and potentially a cough if there's pulmonary involvement, though they are much less common.
    • Leukemia or lymphoma: These conditions can cause a wide range of symptoms including sore throat and cough, and although rare, are critical to diagnose early.
    • Behçet's disease: A rare condition that can cause oral ulcers and potentially other symptoms like cough if there's pulmonary involvement.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.