What is the cause of the patient's abnormal uterine bleeding (AUB) with menorrhagia, and recurrent chest pain with radiation to the abdomen, in a patient with a history of anemia, and previous referrals to gynecology (GYN) and cardiology?

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Differential Diagnosis

The patient presents with two main concerns: abnormal uterine bleeding (AUB) and occasional chest pain. The following differential diagnoses are organized into categories:

  • Single Most Likely Diagnosis

    • Abnormal Uterine Bleeding (AUB) due to hormonal imbalance: The patient's history of prolonged and heavy menstrual bleeding, resulting in anemia, suggests a hormonal imbalance as the most likely cause of her AUB.
    • Gastroesophageal Reflux Disease (GERD): The patient's symptoms of chest pain radiating from the abdomen, burping, and anxiety, especially when considering her history of GI upset, point towards GERD as a likely cause of her chest pain.
  • Other Likely Diagnoses

    • Uterine Fibroids: The patient's history of AUB and anemia could be related to uterine fibroids, which are common in women of reproductive age.
    • Dysmenorrhea: The patient's menstrual cramps and heavy bleeding could be related to dysmenorrhea, a common condition in women.
    • Peptic Ulcer Disease: The patient's symptoms of chest pain and GI upset could be related to peptic ulcer disease, especially considering her history of smoking.
    • Musculoskeletal Chest Pain: The patient's report of chest pain related to posture and her plan to undergo a correction procedure suggests that musculoskeletal chest pain could be a contributing factor.
  • Do Not Miss Diagnoses

    • Coronary Artery Disease: Although the patient denies crushing chest pain and diaphoresis, coronary artery disease must be considered, especially given her history of smoking and multiple ER visits.
    • Pulmonary Embolism: The patient's history of chest pain and anxiety warrants consideration of pulmonary embolism, although her symptoms do not strongly suggest this diagnosis.
    • Ectopic Pregnancy: Although the patient is on Depo-Provera, ectopic pregnancy must be considered in any woman of reproductive age presenting with abdominal pain and bleeding.
  • Rare Diagnoses

    • Endometrial Hyperplasia or Cancer: Although less likely, endometrial hyperplasia or cancer could be a cause of the patient's AUB, especially if she has risk factors such as obesity or a family history.
    • Esophageal Spasm or Achalasia: The patient's symptoms of chest pain and burping could be related to esophageal spasm or achalasia, although these conditions are less common.
    • Cardiac Causes of Chest Pain (e.g., Pericarditis, Cardiomyopathy): Although less likely, other cardiac causes of chest pain must be considered, especially given the patient's history of chest pain and multiple ER visits.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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