What is the cause of facial swelling without recent introduction of new medications or topical lotions (over-the-counter creams or ointments)?

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Differential Diagnosis for Face Swelling

Single Most Likely Diagnosis

  • Allergic Reaction: This is a common cause of face swelling, and the absence of new medications or lotions does not rule out an allergic reaction to food, insect bites, or other environmental allergens.

Other Likely Diagnoses

  • Dental Infection: A dental infection, such as an abscess, can cause swelling of the face, particularly if the infection is located in the upper jaw.
  • Sinusitis: Inflammation of the sinuses can cause swelling of the face, especially if the sinuses are infected.
  • Trauma: A blow to the face can cause swelling, even if the patient does not remember the incident.

Do Not Miss Diagnoses

  • Angioedema: A rare but life-threatening condition that can cause rapid swelling of the face, lips, and airways, potentially leading to respiratory obstruction.
  • Cellulitis: A bacterial infection of the skin that can cause swelling, redness, and warmth of the affected area, and can be serious if left untreated.
  • Lymphoma or Other Malignancy: Although rare, face swelling can be a symptom of lymphoma or other malignancies, such as a parotid gland tumor.

Rare Diagnoses

  • Melkersson-Rosenthal Syndrome: A rare neurological disorder that can cause recurring episodes of facial swelling, particularly of the lips and face.
  • Sarcoidosis: A rare autoimmune disorder that can cause inflammation and swelling in various parts of the body, including the face.
  • Wegener's Granulomatosis: A rare autoimmune disorder that can cause inflammation and swelling of the blood vessels, including those in the face.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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