How should I report high‑flow nasal cannula (HFNC) settings in the medical record?

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Last updated: March 29, 2026 • View editorial policy

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How to Report HFNC Settings in the Medical Record

Document HFNC settings by recording both the flow rate (in L/min) and the fraction of inspired oxygen (FiO2 as a percentage or decimal), as these are the two essential parameters that define the therapy and guide clinical decision-making.

Essential Parameters to Document

When recording HFNC in the medical record, you must include:

  • Flow rate: Document in liters per minute (L/min), typically ranging from 30-60 L/min 1
  • FiO2: Record as either a percentage (e.g., 60%) or decimal (e.g., 0.60) 2

Example Documentation Format

A complete HFNC order or progress note should read:

  • "HFNC at 40 L/min, FiO2 60%"
  • "High-flow nasal cannula: Flow 50 L/min, FiO2 0.50"

Additional Clinical Parameters to Track

Beyond the device settings, document these physiological responses to guide ongoing management:

  • SpO2/FiO2 ratio: This helps assess oxygenation efficiency 2
  • ROX index: Calculate as (SpO2/FiO2)/respiratory rate - a key predictor of HFNC success 2
  • Respiratory rate: Essential for calculating ROX index and monitoring work of breathing 1
  • Patient comfort level: HFNC improves comfort compared to conventional oxygen and NIV 1

Practical Flow Setting Guidance

The evidence suggests a pragmatic approach to initial settings 2:

  • Start at 40 L/min for most patients with acute hypoxemic respiratory failure, as mean peak tidal inspiratory flow (PTIF) in these patients is typically 30-40 L/min
  • Titrate flow upward based on ROX index improvement and patient tolerance
  • The ROX index plateaus when HFNC flow reaches approximately 1.34-1.67 times the patient's individual PTIF

Common Pitfall to Avoid

Many clinicians set initial flows at 45-50 L/min based on convention 3, but starting at 40 L/min and titrating based on physiological response (ROX index) is more evidence-based 2. The key is that HFNC flow should exceed the patient's inspiratory demand to maximize benefit.

Monitoring and Adjustment Documentation

Record changes in settings along with the clinical rationale:

  • Document why flows or FiO2 were adjusted (e.g., "Increased flow from 40 to 50 L/min due to persistent tachypnea and ROX index <4.88")
  • Note patient response to changes within 5-10 minutes 2
  • Track trends in SpO2, respiratory rate, and work of breathing

The standardized documentation of these parameters allows for consistent monitoring and facilitates timely escalation or de-escalation of respiratory support based on objective criteria rather than subjective assessment alone.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.