From the FDA Drug Label
Amoxicillin for oral suspension is indicated in the treatment of infections due to susceptible (ONLY β-lactamase–negative) isolates of Streptococcusspecies. (α-and β-hemolytic isolates only), The recommended antibiotic treatment for Streptococcus salivarius infection is amoxicillin (PO), as it is indicated for the treatment of infections due to susceptible Streptococcus species, including α-and β-hemolytic isolates, which includes Streptococcus salivarius 1.
- The treatment should be continued for a minimum of 48 to 72 hours beyond the time that the patient becomes asymptomatic, or evidence of bacterial eradication has been obtained.
- It is recommended that there be at least 10 days’ treatment for any infection caused by Streptococcus species to prevent the occurrence of acute rheumatic fever.
From the Research
Recommended Antibiotic Treatment for Streptococcus salivarius Infection
There are no specific studies provided that directly address the treatment of Streptococcus salivarius infections. However, the provided studies discuss the treatment of streptococcal pharyngitis, which may be relevant.
Treatment Options for Streptococcal Pharyngitis
- Erythromycin has been shown to be effective in the treatment of streptococcal pharyngitis, with a recommended daily dosage of 20 to 30 mg/kg/day for erythromycin estolate and 40 mg/kg/day for erythromycin ethylsuccinate 2.
- Amoxicillin, administered once daily, has been found to be not inferior to other dosages of the same antibiotic or penicillin V in the treatment of streptococcal pharyngitis 3.
- Penicillin V, in a dosage of 250 mg twice daily for ten days, is considered optimal treatment for children with streptococcal pharyngitis 4.
- Clarithromycin has been shown to be as safe and effective as penicillin VK in the treatment of streptococcal pharyngitis 5.
- Clindamycin has been found to be effective in treating chronic pharyngeal carriage of group A streptococci, with a success rate of 92% 6.
Key Considerations
- The choice of antibiotic treatment may depend on factors such as patient compliance, allergy history, and local resistance patterns.
- Treatment duration and dosage may vary depending on the specific antibiotic and patient population.
- Further research is needed to determine the most effective treatment for Streptococcus salivarius infections specifically.