From the Research
For constipation relief, drink 4-8 ounces (120-240 ml) of prune juice daily, preferably in the morning on an empty stomach, as it has been shown to be effective in improving stool frequency and consistency, and ameliorating subjective complaints of constipation, as demonstrated in a randomized placebo-controlled trial 1.
Key Considerations
- The most recent and highest quality study, published in 2022, found that prune juice containing sorbitol, pectin, and polyphenol ameliorates subjective complaints and hard feces while normalizing stool in chronic constipation 1.
- Prune juice works effectively because it contains sorbitol, a natural sugar alcohol that acts as an osmotic laxative by drawing water into the intestines, and dihydrophenylisatin, which stimulates intestinal contractions, as well as being rich in fiber, which adds bulk to stool.
- Results typically appear within 24-48 hours, and warming the juice slightly may potentially lead to faster results.
- If constipation persists beyond a week or is accompanied by severe pain or bleeding, it is essential to consult a healthcare provider, as this may indicate a more serious condition.
Dosage and Administration
- Start with 4 ounces (120 ml) of prune juice daily and increase gradually as needed, up to 8 ounces (240 ml) twice daily for more severe constipation, while being cautious of potential bloating or diarrhea.
- Prune juice can be consumed on an empty stomach, preferably in the morning, to maximize its effectiveness.
Comparison with Other Treatments
- A 2021 study found that kiwifruit, prunes, and psyllium improve constipation symptoms in patients with chronic constipation, with kiwifruit being associated with the lowest rate of adverse events and dissatisfaction with therapy 2.
- A 2022 systematic review and meta-analysis found that fiber supplementation, particularly psyllium, is effective in improving constipation, with higher doses (>10 g/d) and longer treatment durations (≥4 weeks) appearing optimal 3.