Differential Diagnosis for Allergic Reaction 12 Hours After Peanut Oil Exposure
Single Most Likely Diagnosis
- Anaphylaxis: This is the most likely diagnosis given the symptoms of angioedema and the timing of the reaction after peanut oil exposure. Anaphylaxis is a severe, life-threatening allergic reaction that can occur within minutes of exposure to an allergen, but can also be delayed.
Other Likely Diagnoses
- Urticaria: This is another possible diagnosis, as urticaria (hives) can occur in response to an allergic reaction and may be accompanied by angioedema.
- Atopic Dermatitis: Although less likely, atopic dermatitis (eczema) can be exacerbated by exposure to allergens like peanut oil, leading to skin symptoms.
- Contact Dermatitis: This is a possibility if the peanut oil came into direct contact with the skin, causing a localized allergic reaction.
Do Not Miss Diagnoses
- Hereditary Angioedema: This is a rare genetic disorder that can cause recurrent episodes of angioedema, often without urticaria. It's essential to consider this diagnosis to avoid missing a potentially life-threatening condition.
- Mastocytosis: This condition involves an accumulation of mast cells in the skin and other organs, which can lead to severe allergic reactions, including anaphylaxis.
Rare Diagnoses
- Eosinophilic Esophagitis: Although rare, this condition can cause symptoms similar to anaphylaxis, including angioedema, in response to food allergens like peanut oil.
- Food Protein-Induced Enterocolitis Syndrome (FPIES): This is a rare food allergy that can cause severe symptoms, including vomiting, diarrhea, and abdominal pain, often without urticaria or angioedema.