What is the cause of Maria Barragan's persistent cough, given her past medical history (PMHx) of Hypertension (HTN), Hyperlipidemia (HLD), prediabetes, carotid body paraganglioma, and osteoporosis, and recent hospitalization for hypoxia related to Influenza and pneumonia, with current symptoms of productive cough, expiratory wheezing, and postnasal drip, despite initial improvement with Robitussin (Guaifenesin)?

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Differential Diagnosis for Maria Barragan

  • Single most likely diagnosis
    • Chronic bronchitis: This is the most likely diagnosis given Maria's persistent cough, which has been ongoing for 2 months, and is productive with a clear yellow color. The presence of expiratory wheezing and postnasal drip also supports this diagnosis. Although she denies a history of smoking, she may have been exposed to secondhand smoke or other environmental irritants.
  • Other Likely diagnoses
    • Postnasal drip syndrome: Maria's symptoms of postnasal drip, cough, and expiratory wheezing are consistent with this diagnosis. The fact that her cough worsened at night, particularly when lying down, also supports this diagnosis.
    • Gastroesophageal reflux disease (GERD): GERD can cause a chronic cough, especially at night, and can be exacerbated by lying down. Maria's history of prediabetes and osteoporosis may also increase her risk for GERD.
    • Allergic rhinitis: Although Maria's symptoms initially improved with Robitussin, the fact that her cough worsened again, particularly at night, and is productive with a clear yellow color, may suggest an allergic component.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Pulmonary embolism: Although Maria denies shortness of breath, chest pain, or dizziness, a pulmonary embolism can present with a cough and wheezing. Her history of carotid body paraganglioma and recent hospitalization for hypoxia increase her risk for thromboembolic events.
    • Lung cancer: Although Maria denies a history of smoking, her age and history of carotid body paraganglioma increase her risk for lung cancer. A persistent cough, especially with wheezing and postnasal drip, should prompt further evaluation.
    • Tuberculosis: Although Maria denies any ill contacts, tuberculosis can present with a chronic cough, wheezing, and postnasal drip. Her recent hospitalization and history of hypoxia increase her risk for reactivation of latent tuberculosis.
  • Rare diagnoses
    • Churg-Strauss syndrome: This rare autoimmune disorder can present with a chronic cough, wheezing, and postnasal drip. Maria's history of asthma-like symptoms and eosinophilia (if present) would support this diagnosis.
    • Bronchiectasis: This rare condition can cause a chronic cough, wheezing, and postnasal drip. Maria's history of recurrent infections and hypoxia increase her risk for bronchiectasis.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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