What is Mydayis (amphetamine mixted salts)?

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From the Guidelines

Mydayis is a prescription medication used to treat attention-deficit/hyperactivity disorder (ADHD) in patients 13 years and older, containing a mixture of amphetamine salts in a triple-bead extended-release formulation.

Key Characteristics of Mydayis

  • It is designed to provide symptom control for up to 16 hours, taken once daily in the morning.
  • Starting doses are usually at 12.5 mg for adolescents and 12.5 or 25 mg for adults, which may be adjusted by a healthcare provider based on response and tolerability.
  • The medication works by increasing levels of neurotransmitters like dopamine and norepinephrine in the brain, helping improve attention, focus, and behavioral control in people with ADHD.

Important Considerations

  • As a stimulant medication, Mydayis carries risks including potential for abuse, cardiovascular effects, and psychiatric side effects, and it may interact with certain medications 1.
  • Common side effects include decreased appetite, insomnia, dry mouth, and increased heart rate.
  • Patients should avoid taking Mydayis with MAO inhibitors and should disclose all medications they're taking to their healthcare provider.

Clinical Guidelines and Recommendations

  • According to recent studies, stimulant medications like Mydayis are first-line treatments for ADHD due to their efficacy and safety profile 1.
  • However, it's crucial to weigh the benefits against potential risks, especially in patients with preexisting conditions or those taking other medications.
  • Regular monitoring of pulse, blood pressure, and potential side effects is recommended when prescribing Mydayis 1.

From the Research

Definition and Overview of Mydayis

  • Mydayis is a medication used to treat Attention Deficit Hyperactivity Disorder (ADHD) 2.
  • It is a psychostimulant, which works by increasing the levels of certain neurotransmitters in the brain, such as dopamine and norepinephrine 2.
  • Mydayis is a combination of dextroamphetamine and amphetamine, which are both stimulants commonly used to treat ADHD 3, 2.

Mechanism of Action

  • The primary pharmacologic effect of Mydayis is to increase central dopamine and norepinephrine activity, which impacts executive and attentional function 2.
  • Mydayis actions include dopamine and norepinephrine transporter inhibition, vesicular monoamine transporter 2 (VMAT-2) inhibition, and monoamine oxidase activity inhibition 2.

Side Effects and Risks

  • Common side effects of Mydayis include loss of appetite, sleep problems, and mood disturbances 4.
  • Misuse of stimulants like Mydayis can be associated with dangers including psychosis, myocardial infarction, cardiomyopathy, and even sudden death 5.
  • Long-term safety studies and education on the health risks associated with misuse of Mydayis are imperative 5.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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