From the Guidelines
Ozempic (semaglutide) should be refrigerated before its first use, but after first use, it can be stored at room temperature not exceeding 86°F (30°C) for up to 56 days (8 weeks) 1. The storage requirements for Ozempic are crucial to maintain its effectiveness, as it is a peptide-based medication that can degrade when exposed to higher temperatures.
- Before first use, Ozempic should be refrigerated at a temperature between 36°F to 46°F (2°C to 8°C) to prevent degradation.
- After first use, there are two storage options: continue refrigerating it or keep it at room temperature not exceeding 86°F (30°C) for up to 56 days (8 weeks) 1.
- It is essential to never freeze Ozempic and always protect it from direct heat and light.
- The medication comes with a built-in temperature indicator on the pen, and if the liquid appears cloudy, discolored, or contains particles, it may have been compromised by improper storage and should not be used 1. When traveling, consider using a medication cooler or insulated bag with ice packs to maintain the proper temperature, especially for longer trips or in hot weather. Key points to consider when storing Ozempic include:
- Refrigeration before first use
- Storage at room temperature after first use
- Avoiding freezing and direct heat
- Protecting from light
- Checking the medication for signs of degradation before use 1.
From the FDA Drug Label
Prior to first use, OZEMPIC should be stored in a refrigerator between 36ºF to 46ºF (2ºC to 8ºC). Do not store in the freezer or directly adjacent to the refrigerator cooling element. Do not freeze OZEMPIC and do not use OZEMPIC if it has been frozen After first use of the OZEMPIC pen, the pen can be stored for 56 days at controlled room temperature (59°F to 86°F; 15°C to 30°C) or in a refrigerator (36°F to 46°F; 2°C to 8°C).
Ozempic Storage Requirements:
- Before first use, Ozempic must be stored in the refrigerator at a temperature between 36°F to 46°F (2°C to 8°C) 2.
- After first use, Ozempic can be stored at room temperature (59°F to 86°F; 15°C to 30°C) or in the refrigerator for up to 56 days 2.
- Do not freeze Ozempic, as this can affect its potency and safety 2.
From the Research
Storage and Handling of Ozempic
- Ozempic, which contains the active ingredient semaglutide, is typically administered via injection and comes in a pre-filled pen or syringe.
- According to the studies provided, there is no direct information on whether Ozempic needs to be stored in a cold environment 3, 4, 5, 6, 7.
- However, it is common practice to store injectable medications, including Ozempic, in the refrigerator to maintain their potency and shelf life.
- It is recommended to consult the packaging or labeling of Ozempic for specific storage and handling instructions, as these may vary depending on the manufacturer and formulation.
Importance of Proper Storage and Handling
- Proper storage and handling of Ozempic are crucial to ensure its efficacy and safety.
- Improper storage or handling can affect the stability and potency of the medication, which may impact its ability to control blood sugar levels.
- Patients should follow the recommended storage and handling instructions for Ozempic to minimize the risk of adverse effects or reduced efficacy 3, 4, 5, 6, 7.