From the Guidelines
Clotrimazole is the preferred treatment option for fungal infections due to its established efficacy, lower cost, and extensive clinical research supporting its use, as compared to Terrasil which has less robust clinical evidence supporting its effectiveness. Terrasil and clotrimazole are both antifungal treatments, but they differ in composition and application. Terrasil is a branded product containing multiple ingredients including natural minerals, essential oils, and often jojoba oil or beeswax, along with an active antifungal component (sometimes silver oxide). Clotrimazole is a specific antifungal medication available as a generic prescription or over-the-counter product.
Key Differences
- Clotrimazole is typically applied 2-3 times daily for 2-4 weeks depending on the infection type, while Terrasil's application instructions vary by product.
- Clotrimazole works by disrupting the fungal cell membrane, preventing fungal growth and reproduction.
- Terrasil claims to work through its proprietary blend of ingredients, but has less robust clinical evidence supporting its effectiveness compared to clotrimazole.
Clinical Evidence
According to the clinical practice guidelines for the management of candidiasis 1, clotrimazole is a recommended treatment option for vulvovaginal candidiasis, and its use is supported by extensive clinical research. In contrast, there is limited clinical evidence supporting the effectiveness of Terrasil for fungal infections.
Treatment Recommendations
For most common fungal infections like athlete's foot, ringworm, or yeast infections, clotrimazole is typically recommended as the first-line treatment due to its established efficacy, lower cost, and extensive clinical research supporting its use. If you're considering treatment for a fungal infection, consult with a healthcare provider who can recommend the most appropriate option based on your specific condition.