What is the differential diagnosis for a 16-year-old female with a history of Gastroesophageal Reflux Disease (GERD) who presents with a recent history of pharyngitis, cough, and nasal congestion that improved, followed by a week of intractable vomiting?

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Differential Diagnosis for a 16-year-old Female with GERD, Sore Throat, Cough, Congestion, and Intractable Vomiting

  • Single Most Likely Diagnosis
    • Gastroesophageal reflux disease (GERD) exacerbation: The patient's history of GERD and symptoms of intractable vomiting suggest that her condition may have worsened, leading to increased reflux and subsequent vomiting.
  • Other Likely Diagnoses
    • Viral gastroenteritis: Although the patient's initial symptoms of sore throat, cough, and congestion improved, the onset of intractable vomiting could be indicative of a viral gastrointestinal infection.
    • Gastritis: Inflammation of the stomach lining could be causing the patient's vomiting, especially if she has a history of GERD or has been taking nonsteroidal anti-inflammatory drugs (NSAIDs).
    • Peptic ulcer disease: A peptic ulcer could be causing the patient's vomiting, especially if she has a history of GERD or has been taking NSAIDs.
  • Do Not Miss Diagnoses
    • Appendicitis: Although the patient's symptoms do not typically suggest appendicitis, it is a potentially life-threatening condition that requires prompt diagnosis and treatment.
    • Intestinal obstruction: A bowel obstruction could be causing the patient's vomiting, and it is essential to rule out this condition to prevent complications.
    • Ectopic pregnancy: Although the patient is only 16, it is crucial to consider the possibility of pregnancy, especially if she is sexually active.
    • Inflammatory bowel disease (IBD): Conditions like Crohn's disease or ulcerative colitis could be causing the patient's symptoms, and it is essential to rule out these conditions to provide appropriate treatment.
  • Rare Diagnoses
    • Cyclic vomiting syndrome: A rare condition characterized by recurrent episodes of severe vomiting, which could be a possibility if the patient's symptoms are episodic.
    • Rumination syndrome: A condition where food is regurgitated and then re-chewed, which could be a possibility if the patient has a history of eating disorders or gastrointestinal issues.
    • Gastric volvulus: A rare condition where the stomach twists, which could be causing the patient's vomiting, although it is unlikely.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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