Differential Diagnosis for Water Blister near Head of Penis
- Single most likely diagnosis
- Genital herpes: This is a common sexually transmitted infection that can cause painful blisters or sores on the genitals, including the head of the penis. The presence of a water blister near this area is highly suggestive of this diagnosis.
- Other Likely diagnoses
- Friction blister: Friction from sexual activity, tight clothing, or other sources can cause blisters on the penis, including the head.
- Contact dermatitis: An allergic reaction or irritation from soaps, lotions, or other substances can lead to blisters and skin lesions on the genital area.
- Fixed drug eruption: A type of drug reaction that can cause blisters or lesions on the skin, including the genital area, in response to certain medications.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Syphilis: Although less common, syphilis can cause a painless sore or blister on the genitals, including the head of the penis, and if left untreated, can lead to serious complications.
- Penile cancer: Although rare, any unusual or persistent lesion on the penis should be evaluated for the possibility of cancer.
- Rare diagnoses
- Bullous pemphigoid: A rare autoimmune disorder that can cause blisters on the skin, including the genital area.
- Pemphigus: Another rare autoimmune disorder that can cause blisters on the skin and mucous membranes, including the genital area.
- Aphthous ulcers: Although more common in the mouth, aphthous ulcers can occasionally occur on the genitals, including the head of the penis, and can cause significant discomfort.