What is the cause of an elderly man's symptoms, including asthenia (weakness), lethargy, and a 2-week history of hematochezia (blood streaks in the stool), with laboratory results showing anemia (low hemoglobin) and a physical examination revealing a hemorrhoid (pile), given the differential diagnoses of sigmoid cancer, rectal cancer (secondary to hemorrhoids), and cecal cancer?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 5, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Elderly Man with Asthenia, Lethargy, and Blood Streaks in Stool

  • Single Most Likely Diagnosis
    • Rectal Cancer (2ry piles): The presence of piles (hemorrhoids) along with blood streaks in the stool and low hemoglobin levels could indicate that the hemorrhoids are secondary to a rectal cancer, which is causing obstruction and leading to hemorrhoids. The symptoms of asthenia and lethargy could be due to anemia resulting from chronic blood loss.
  • Other Likely Diagnoses
    • Sigmoid Cancer: Similar to rectal cancer, sigmoid cancer could cause blood in the stool and lead to anemia, asthenia, and lethargy. However, it might be less likely to cause secondary piles compared to rectal cancer due to its location.
    • Caecal Cancer: Although less common to present with visible blood in the stool compared to left-sided colon cancers like sigmoid or rectal cancer, caecal cancer could still lead to anemia and similar symptoms. The blood might be occult, but the presence of visible blood streaks makes this less likely.
  • Do Not Miss Diagnoses
    • Colonic Angiodysplasia: This condition involves vascular malformations in the colon that can cause chronic blood loss, leading to anemia and potentially similar symptoms. It's crucial not to miss this diagnosis as it requires specific management.
    • Inflammatory Bowel Disease (IBD): Conditions like Crohn's disease or ulcerative colitis could present with blood in the stool, anemia, and systemic symptoms like asthenia and lethargy. Missing this diagnosis could lead to delayed treatment and worsening of the condition.
  • Rare Diagnoses
    • Intestinal Lymphoma: Although rare, intestinal lymphoma could present with similar symptoms, including anemia, weight loss, and gastrointestinal bleeding. It's essential to consider this in the differential diagnosis, especially if other causes are ruled out.
    • Dieulafoy's Lesion: A rare cause of gastrointestinal bleeding, Dieulafoy's lesion is a vascular malformation that can cause significant blood loss. It's an important consideration in cases where the source of bleeding is not immediately apparent.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.