Is a testosterone level of 23 ng/dL adequate during perimenopause?

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From the Research

A testosterone level of 23 ng/dL during perimenopause is considered on the lower end of the normal range for women, and supplementation may be considered if symptoms are present, as supported by the most recent study 1. Normal female testosterone levels typically range from 15-70 ng/dL, so while your level is within range, it's on the lower side. Some key points to consider:

  • If you're experiencing symptoms like decreased libido, fatigue, mood changes, or difficulty maintaining muscle mass, your healthcare provider might consider testosterone supplementation.
  • Options could include compounded testosterone creams (typically 0.5-2 mg daily applied to the skin) or FDA-approved testosterone products used off-label at lower doses appropriate for women.
  • Before starting any treatment, comprehensive hormone testing is recommended, including estradiol, progesterone, DHEA-S, and complete thyroid panel, as these hormones work together.
  • Testosterone plays important roles in women's health beyond sexual function, including maintaining bone density, muscle mass, energy levels, and cognitive function.
  • During perimenopause, declining ovarian function can lead to decreased testosterone production, which may contribute to various symptoms, as noted in earlier studies 2, 3. Always consult with a healthcare provider experienced in hormone management before starting any treatment, and consider the potential risks and benefits as outlined in the guidelines 4, 5.

References

Research

Practical Approach to Hyperandrogenism in Women.

The Medical clinics of North America, 2021

Research

Testosterone therapy in premenopausal women.

Seminars in reproductive medicine, 2006

Research

Treatment of hirsutism and acne in hyperandrogenism.

Best practice & research. Clinical endocrinology & metabolism, 2006

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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