What is the cause of a patient's acute right knee pain, worsened by walking and straightening, with a history of degenerative changes, effusion, and a previous cortisone shot, unrelieved by Tylenol (acetaminophen)?

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Differential Diagnosis for 1-Day Left Knee Pain

  • Single most likely diagnosis
    • Meniscal tear: The patient's sudden onset of knee pain, worsening with walking and straightening, and improvement with slight bending, is consistent with a meniscal tear. The history of a cortisone shot many years ago and degenerative changes on x-ray also support this diagnosis.
  • Other Likely diagnoses
    • Ligament sprain: The patient's description of their knee "going out to the side" could indicate a ligament sprain, which is a common injury that can occur with sudden twisting or bending.
    • Osteoarthritis flare: The patient's history of degenerative changes and previous cortisone shot suggests osteoarthritis, and the current symptoms could represent a flare of this condition.
    • Patellofemoral pain syndrome: The patient's pain worsening with walking and straightening, and improvement with slight bending, could also be consistent with patellofemoral pain syndrome.
  • Do Not Miss diagnoses
    • Septic arthritis: Although less likely, septic arthritis is a serious condition that requires prompt diagnosis and treatment. The patient's sudden onset of pain and lack of relief with Tylenol could be consistent with septic arthritis.
    • Fracture: A fracture, such as a stress fracture or osteochondral fracture, could also present with sudden onset of pain and should not be missed.
  • Rare diagnoses
    • Osteonecrosis: The patient's history of cortisone shot and degenerative changes could increase the risk of osteonecrosis, although this is a less common condition.
    • Rheumatologic conditions: Conditions such as rheumatoid arthritis or lupus could also present with knee pain, although these are less likely given the patient's history and presentation.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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