What is the differential diagnosis of Lichen Planus Pigmentosus (LPP)?

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Differential Diagnosis for Lichen Planus Pigmentosus

  • Single most likely diagnosis
    • Melasma: This condition is characterized by patches of discoloration, typically on the face, and can be mistaken for lichen planus pigmentosus due to the similar presentation of hyperpigmentation.
  • Other Likely diagnoses
    • Post-inflammatory hyperpigmentation (PIH): This condition occurs after inflammation or injury to the skin, leading to areas of hyperpigmentation that can resemble lichen planus pigmentosus.
    • Erythema dyschromicum perstans: A condition that presents with asymptomatic, progressive, and persistent hyperpigmentation, which can be difficult to distinguish from lichen planus pigmentosus.
    • Ashy dermatosis: Characterized by grayish-brown patches on the face, neck, and arms, which can be similar in appearance to lichen planus pigmentosus.
  • Do Not Miss
    • Addison's disease: Although rare, this condition can cause hyperpigmentation and must be considered due to its potential severity and the need for prompt treatment.
    • Hemochromatosis: A genetic disorder that can lead to skin hyperpigmentation, among other symptoms, and requires early diagnosis to prevent complications.
  • Rare diagnoses
    • Arsenic poisoning: Can cause hyperpigmentation, among other skin manifestations, and is essential to consider due to its potential toxicity.
    • Fixed drug eruption: A condition that can present with hyperpigmentation after resolution of the eruption, which might be mistaken for lichen planus pigmentosus.
    • Pigmented contact dermatitis: A rare condition that can cause hyperpigmentation due to an allergic reaction to certain substances.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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