From the Guidelines
Ketoprofen is an NSAID (non-steroidal anti-inflammatory drug). It belongs to the propionic acid class of NSAIDs and works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), which reduces the production of prostaglandins responsible for inflammation, pain, and fever. Ketoprofen is available in various formulations including oral tablets, capsules, extended-release forms, and topical preparations. Common dosages for adults typically range from 50-200 mg daily, divided into multiple doses, though specific dosing depends on the condition being treated and individual factors. Like other NSAIDs, ketoprofen carries risks of gastrointestinal side effects (stomach ulcers, bleeding), cardiovascular risks with long-term use, and kidney effects. It should be used at the lowest effective dose for the shortest duration necessary, and patients with certain conditions like heart disease, kidney problems, or history of stomach ulcers should use it with caution or avoid it altogether 1.
Key Points
- Ketoprofen is classified as an NSAID, specifically a propionic acid derivative 1
- It is used to treat pain, inflammation, and fever by inhibiting COX-1 and COX-2 enzymes 1
- Common dosages range from 50-200 mg daily, but specific dosing depends on the condition and individual factors 1
- Risks associated with ketoprofen include gastrointestinal side effects, cardiovascular risks, and kidney effects 1
- Patients with certain conditions should use ketoprofen with caution or avoid it altogether 1
Recommendations
- Use ketoprofen at the lowest effective dose for the shortest duration necessary to minimize risks 1
- Consider alternative treatments for patients with certain conditions, such as heart disease, kidney problems, or history of stomach ulcers 1
- Monitor patients for signs of gastrointestinal side effects, cardiovascular risks, and kidney effects while taking ketoprofen 1
From the FDA Drug Label
Ketoprofen is a non-steroidal anti-inflammatory drug. The answer to the question is yes, ktoproffen (ketoprofen) is an NSAID 2.
From the Research
Definition of NSAID
- A nonsteroidal anti-inflammatory drug (NSAID) is a type of medication that reduces inflammation and relieves pain [(3,4,5,6,7)].
Classification of Ketoprofen
- Ketoprofen is classified as a nonsteroidal anti-inflammatory drug (NSAID) [(3,4,5,6,7)].
- It belongs to the 2-arylpropionic acid class of NSAIDs 3.
- Ketoprofen is also a propionic acid derivative [(5,6)].
Properties of Ketoprofen
- Ketoprofen has anti-inflammatory, analgesic, and antipyretic properties [(3,4,5,6)].
- It has a short half-life and a simple metabolism 5.
- Ketoprofen exhibits little stereoselectivity in its pharmacokinetics 3.
Uses of Ketoprofen
- Ketoprofen is used to treat rheumatoid arthritis, osteoarthritis, and other inflammatory conditions [(3,4,5,7)].
- It is also used to treat acute and chronic pain, including postoperative pain [(4,7)].
- Ketoprofen has been shown to be effective in the prophylaxis of heterotopic calcification following hip or pelvic major intervention 4.