From the FDA Drug Label
HYDROQUINONE USP, 4% SKIN BLEACHING CREAM should be applied to affected areas and rubbed in well twice daily, in the morning and before bedtime, or as directed by a physician. HYDROQUINONE USP, 4% SKIN BLEACHING CREAM is indicated for the gradual bleaching of hyperpigmented skin conditions such as ... senile lentigines, and other unwanted areas of melanin hyperpigmentation. To apply Pigmanorm (hydroquinone) for lentigines,
- Apply the cream to the affected areas
- Rub in well
- Apply twice daily, in the morning and before bedtime
- Or as directed by a physician [1] [2]
From the Research
To apply Pigmanorm for lentigines, first wash and dry the affected area thoroughly and apply a thin layer of Pigmanorm cream directly to the lentigines once or twice daily as prescribed by your doctor, typically in the evening, while being aware that combination-based treatments and laser-based treatments have shown the greatest efficacy in treating lentigines, as reported in the most recent study 3. When using Pigmanorm for lentigines, it is essential to follow the prescribed application regimen and take necessary precautions to minimize potential side effects.
- Apply a thin layer of Pigmanorm cream directly to the lentigines (brown spots) once or twice daily, typically in the evening.
- Avoid applying to unaffected skin.
- Gently massage the cream until absorbed.
- Wash your hands immediately after application.
- Use the medication consistently for 8-12 weeks, as results develop gradually. During treatment, it is crucial to protect your skin from the sun, as Pigmanorm can increase sun sensitivity.
- Apply sunscreen (SPF 30+) daily.
- Limit sun exposure. If you experience severe irritation, redness, or burning, discontinue use and consult your doctor. Pigmanorm contains a combination of hydroquinone, tretinoin, and hydrocortisone that works by inhibiting melanin production, promoting skin cell turnover, and reducing inflammation, effectively lightening the dark spots over time, with some mild redness or peeling being normal during initial treatment as your skin adjusts to the medication, as supported by earlier studies 4, 5, 6, 7.