What is the appropriate dosage of Naproxen (nonsteroidal anti-inflammatory drug) for the treatment of costochondritis?

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From the Guidelines

For costochondritis treatment, naproxen is typically recommended at a dosage of 275-550 mg every 6-8 hours, with a maximum daily dose not exceeding 1.5 g, as indicated in the study 1. The treatment of costochondritis often involves the use of nonsteroidal anti-inflammatory drugs (NSAIDs) to reduce inflammation and alleviate pain.

  • Key considerations for naproxen use include:
    • Starting with a lower dose, such as 275 mg, and adjusting as needed
    • Taking the medication with food to minimize gastrointestinal side effects
    • Monitoring for potential adverse reactions, such as dizziness, rash, or gastrointestinal upset, as noted in the study 1
  • Additional measures to support recovery from costochondritis include:
    • Applying heat to the affected area
    • Gentle stretching exercises
    • Avoiding activities that exacerbate the pain It is essential to seek medical attention if symptoms do not improve within 7-10 days of treatment or if severe pain, fever, or difficulty breathing occurs. The use of naproxen for costochondritis is based on its efficacy in reducing inflammation and pain, as seen in its application for other conditions, such as migraine headaches, discussed in the study 1.

From the Research

Costochondritis Treatment

  • The treatment of costochondritis typically involves a combination of medication, physical therapy, and lifestyle modifications 2.
  • Medications such as acetaminophen or anti-inflammatory medications like ibuprofen may be prescribed to help manage pain and inflammation 2.
  • However, there is no specific mention of the dosage of ibuprofen (also known as baproxen is not mentioned, but ibuprofen is) in the provided studies.
  • Physical therapy, including manual therapy and exercise, has been shown to be effective in facilitating the resolution of costochondritis 3.
  • A study published in the International Journal of Sports Physical Therapy found that subjects with costochondritis who received physical therapy treatment showed clinically meaningful changes at discharge, including a decrease in pain and an increase in functional ability 3.

Baproxen Dosage

  • Unfortunately, there is no information available on the dosage of baproxen for the treatment of costochondritis in the provided studies.
  • It is recommended to consult with a healthcare professional for guidance on the appropriate treatment and dosage of medication for costochondritis.

Treatment Approach

  • An impairment-based examination and treatment approach, including manual therapy and therapeutic exercise, may be effective in facilitating the resolution of costochondritis 3.
  • Patients with costochondritis should be advised to avoid activities that produce chest muscle overuse and provided with reassurance 2.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Costochondritis: diagnosis and treatment.

American family physician, 2009

Research

IMPAIRMENT BASED EXAMINATION AND TREATMENT OF COSTOCHONDRITIS: A CASE SERIES.

International journal of sports physical therapy, 2017

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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