From the FDA Drug Label
MECLIZINE HYDROCHLORIDE tablets, for oral use Initial U. S. Approval: 1957 INDICATIONS AND USAGE Meclizine hydrochloride tablets are indicated for the treatment of vertigo associated with diseases affecting the vestibular system in adults (1).
The treatment for Vestibular Neuritis/Labyrinthitis may involve the use of meclizine to alleviate vertigo associated with these conditions.
- Meclizine is indicated for the treatment of vertigo associated with diseases affecting the vestibular system in adults.
- The recommended dosage is 25 mg to 100 mg daily, in divided doses 1.
- It is essential to use caution when driving a car or operating dangerous machinery, as meclizine may cause drowsiness.
- Patients with a history of asthma, glaucoma, or enlargement of the prostate gland should be prescribed meclizine with care due to its potential anticholinergic action.
From the Research
Treatment for vestibular neuritis and labyrinthitis should focus on managing symptoms while the body heals naturally, with a short course of corticosteroids such as prednisone (60mg daily for 5 days, then tapering over 5 more days) prescribed within the first 3 days of symptom onset to reduce inflammation of the vestibular nerve, as recommended by the most recent study 2. The goal of treatment is to alleviate symptoms, promote recovery, and improve quality of life. Initially, medications like meclizine (25mg every 4-6 hours), diazepam (2-5mg every 6-8 hours), or promethazine (25mg every 4-6 hours) can help control vertigo and nausea for the first few days. Some key points to consider in treatment include:
- The use of antivirals like acyclovir if a herpes virus is suspected
- Bed rest during severe symptoms
- Beginning vestibular rehabilitation exercises as soon as possible, usually within days of onset, to help the brain compensate for the damaged vestibular system
- Including gaze stabilization, balance training, and habituation exercises in the rehabilitation program
- Avoiding driving or operating heavy machinery when experiencing dizziness, staying hydrated, and making slow, controlled movements to minimize vertigo episodes, as supported by studies 3, 4. It is essential to note that the condition is usually self-limiting, with the inflammatory process resolving on its own as the body fights off the underlying viral infection, and most patients see significant improvement within 2-3 weeks, though complete recovery may take 6-8 weeks.