From the Research
Nexplanon does not have a specific weight limit for use, and it remains effective for all body weights, although it may be slightly less effective in women weighing over 130 kg (286 pounds). The implant works by releasing etonogestrel, a synthetic progestin, which prevents pregnancy primarily by inhibiting ovulation 1. Unlike some hormonal contraceptives that have clear weight restrictions, Nexplanon is generally considered appropriate for women of all sizes. However, individuals with certain medical conditions like liver disease, breast cancer, or unexplained vaginal bleeding should discuss these issues with their healthcare provider before choosing Nexplanon. Some studies have evaluated the effectiveness of Nexplanon beyond its approved duration, showing that it continues to be highly effective for at least 2 additional years of use 2. Serum etonogestrel levels have been found to remain above the ovulation threshold of 90 pg/mL for women in all body mass index classes 2. A systematic review on the clinical effectiveness, side-effect profile, and meta-analysis on continuation rate of etonogestrel contraceptive implant found that Nexplanon is clinically effective and safe to use, although 1-year continuation rates are lower compared to other long-acting reversible contraceptives 1. Key points to consider when using Nexplanon include:
- It is effective for all body weights, with slight reduction in efficacy in women over 130 kg
- It works by releasing etonogestrel, which prevents pregnancy by inhibiting ovulation
- It is generally considered appropriate for women of all sizes, but certain medical conditions may require discussion with a healthcare provider
- It continues to be highly effective for at least 2 additional years of use beyond its approved duration
- Serum etonogestrel levels remain above the ovulation threshold for women in all body mass index classes. If you're concerned about contraceptive efficacy related to your weight, consult with your healthcare provider who can help determine if Nexplanon is the best option for your specific situation 3.