Differential Diagnosis for Small White Papular Lesions on Face
- Single Most Likely Diagnosis
- Milia: These are small, white, or yellowish bumps that appear on the skin, often on the face. They are caused by keratin that is trapped beneath the surface of the skin and are very common, especially in infants and adults.
- Other Likely Diagnoses
- Sebaceous hyperplasia: This condition involves the enlargement of sebaceous glands, which can appear as small, white or yellowish bumps on the face.
- Fordyce spots: These are small, white or yellowish bumps that can appear on the face, particularly on the lips, inside of the cheeks, and on the genitalia. They are caused by the abnormal presence of sebaceous glands in the mucous membranes.
- Keratosis pilaris: This is a condition characterized by the appearance of small, white or flesh-colored bumps on the skin, often on the face, arms, and legs. It is caused by the buildup of keratin, a protein that protects the skin from damage.
- Do Not Miss Diagnoses
- Basal cell carcinoma: Although less likely, it's crucial to consider basal cell carcinoma, especially if the lesion is solitary, growing, or has an unusual appearance. Early detection is key for effective treatment.
- Squamous cell carcinoma: Similar to basal cell carcinoma, squamous cell carcinoma can sometimes present as a small, white papule, especially in sun-exposed areas.
- Rare Diagnoses
- Trichoepithelioma: A rare, benign tumor of the hair follicle that can appear as small, white or flesh-colored bumps on the face.
- Syringoma: A rare, benign tumor of the sweat glands that can appear as small, white or yellowish bumps on the face, particularly around the eyes.
- Multiple trichoepitheliomas or other genetic syndromes: In some cases, small white papular lesions on the face can be a sign of a genetic syndrome, such as multiple trichoepitheliomas or Brooke-Spiegler syndrome.