What is the diagnosis and treatment for a 9-year-old female with a tick bite, now presenting with a bullseye pattern rash, and allergies to Clav (clavulanate) and Sulfa (sulfonamide) antibiotics?

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Differential Diagnosis for a 9-year-old female with a tick bite and bullseye pattern rash, allergic to clav and sulfa abx

  • Single most likely diagnosis:
    • Lyme disease: This is the most likely diagnosis given the classic bullseye rash (erythema migrans) following a tick bite, which is a hallmark symptom of Lyme disease.
  • Other Likely diagnoses:
    • Southern tick-associated rash illness (STARI): Although less common than Lyme, STARI can also present with a similar rash after a tick bite, primarily in the southern United States.
    • Tick-borne relapsing fever: This condition, caused by various Borrelia species, can present with fever, headache, and a rash, but the rash is not typically a bullseye pattern.
  • Do Not Miss diagnoses:
    • Rocky Mountain spotted fever (RMSF): Although the rash in RMSF is typically more widespread and petechial, it's crucial to consider this diagnosis due to its high mortality rate if untreated. The presence of a fever, headache, and rash after a tick bite warrants consideration of RMSF.
    • Ehrlichiosis/Anaplasmosis: These tick-borne illnesses can present with fever, headache, and sometimes a rash, and can be severe if not treated promptly.
  • Rare diagnoses:
    • Babesiosis: A parasitic disease transmitted by ticks, babesiosis can cause fever, fatigue, and sometimes a rash, but it's less common and typically presents with more systemic symptoms.
    • Tularemia: Caused by Francisella tularensis, tularemia can be transmitted by tick bites and presents with a skin ulcer, fever, and lymphadenopathy, but it's relatively rare and the rash is not typically a bullseye pattern.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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