What is the differential diagnosis for left lower quadrant (LLQ) abdominal pain?

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Differential Diagnosis for Left Lower Quadrant (LLQ) Abdominal Pain

Single Most Likely Diagnosis

  • Diverticulitis: This is a common cause of LLQ pain, especially in older adults. The pain is usually constant and accompanied by changes in bowel habits, fever, and tenderness in the LLQ.

Other Likely Diagnoses

  • Irritable Bowel Syndrome (IBS): IBS can cause recurrent abdominal pain, often in the LLQ, accompanied by changes in bowel habits, bloating, and gas.
  • Constipation: Severe constipation can cause significant LLQ pain, especially if there is a large fecal impaction.
  • Ovarian Cyst or Torsion: In females, ovarian cysts or torsion can cause severe LLQ pain, often accompanied by nausea, vomiting, and fever.
  • Kidney Stone: A kidney stone in the left ureter can cause severe LLQ pain, radiating to the groin, accompanied by nausea, vomiting, and hematuria.

Do Not Miss Diagnoses

  • Appendicitis (if appendix is in a retrocecal position): Although appendicitis typically presents with right lower quadrant pain, a retrocecal appendix can cause LLQ pain. Missing this diagnosis can lead to perforation and peritonitis.
  • Ectopic Pregnancy: In females of childbearing age, ectopic pregnancy can cause severe LLQ pain, vaginal bleeding, and syncope. Missing this diagnosis can be life-threatening.
  • Inflammatory Bowel Disease (IBD): Crohn's disease or ulcerative colitis can cause chronic LLQ pain, diarrhea, weight loss, and fever. Missing this diagnosis can lead to complications like bowel obstruction or toxic megacolon.
  • Sigmoid Volvulus: A sigmoid volvulus can cause severe LLQ pain, abdominal distension, and constipation. Missing this diagnosis can lead to bowel ischemia and perforation.

Rare Diagnoses

  • Intussusception: A rare cause of LLQ pain, intussusception occurs when a portion of the intestine telescopes into another portion, causing bowel obstruction and ischemia.
  • Colonic Cancer: Although rare in younger adults, colonic cancer can cause LLQ pain, changes in bowel habits, and weight loss.
  • Endometriosis: In females, endometriosis can cause chronic LLQ pain, dysmenorrhea, and dyspareunia.
  • Intra-abdominal Testicular Torsion: A rare cause of LLQ pain in males, intra-abdominal testicular torsion can cause severe pain, nausea, and vomiting.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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