From the Research
For constipation, the recommended dose of mineral oil is not explicitly stated in the most recent and highest quality study, but based on the available evidence, a typical adult dose is 15 to 45 ml (1 to 3 tablespoons) taken orally once daily, usually at bedtime, as seen in previous guidelines 1. However, the most recent study 2 does not provide specific guidance on the dose of mineral oil for constipation, instead focusing on the efficacy and safety of over-the-counter therapies for chronic constipation. Another study 3 compared liquid paraffin (mineral oil) with lactulose and found a significant difference in the number of stools per week favoring liquid paraffin, but did not specify the optimal dose. Considering the potential risks and benefits, it is essential to use mineral oil with caution and under medical supervision, especially in children and older adults. Some key points to consider when using mineral oil for constipation include:
- Taking the oil on an empty stomach, at least 2 hours after eating
- Avoiding use for more than a week without medical supervision
- Not taking mineral oil with meals to prevent reduced absorption of fat-soluble vitamins
- Avoiding use when lying down to prevent accidental inhalation into the lungs
- Consulting a healthcare provider if constipation persists beyond a week or if rectal bleeding or severe abdominal pain occurs. It is crucial to prioritize the patient's morbidity, mortality, and quality of life when making treatment decisions, and to consider the potential risks and benefits of mineral oil and other therapies for constipation 2, 3.