What is the management of seborrheic keratosis?

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Last updated: May 7, 2025View editorial policy

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From the Research

Seborrhoeic keratosis management is primarily focused on removal when necessary, as these benign skin growths don't require treatment unless they cause discomfort, irritation, or cosmetic concerns. The main treatment options include cryotherapy with liquid nitrogen, which freezes the lesion causing it to blister and fall off within days to weeks; curettage and electrocautery, where the growth is scraped off and the base cauterized; shave excision, which removes the raised portion of the lesion; and laser therapy for multiple lesions. Some key points to consider in management decisions include:

  • Lesion characteristics
  • Patient discomfort
  • Cosmetic concerns
  • The potential for post-procedure depigmentation, scarring, and recurrence 1
  • The use of topical agents, such as hydrogen peroxide 40% solution (Eskata), for smaller lesions 2
  • The importance of avoiding picking or scratching these growths, as this can lead to infection or bleeding 3 According to the most recent study, a topical mixture of antioxidants, hydrating, and keratolytic agents may also be effective in improving the appearance of seborrheic keratosis 4. However, the most effective treatment approach should be based on the latest evidence and individual patient needs, with a focus on minimizing morbidity, mortality, and optimizing quality of life. In terms of specific treatment modalities, the choice of treatment should be guided by the lesion's characteristics, patient preferences, and the potential risks and benefits of each option, as outlined in recent studies 5, 1, 2.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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