What is the diagnosis for a small cyst-like lesion under the tongue on the floor of the mouth?

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Differential Diagnosis for Tiny Cyst-like Structure under the Tongue

  • Single most likely diagnosis
    • Mucocele: This is a common, benign condition characterized by a mucus-filled cyst that can occur under the tongue, often resulting from a blocked salivary gland duct. The location and description provided match this diagnosis closely.
  • Other Likely diagnoses
    • Ranula: A type of mucocele that specifically occurs under the tongue, often appearing as a blue, translucent swelling. It's similar to a mucocele but tends to be larger and more noticeable.
    • Salivary gland cyst or benign tumor: These can present as small, cyst-like structures under the tongue and are related to the salivary glands.
    • Fordyce granules: While not typically described as cyst-like, these small, yellowish or white bumps on the lips, inside of the cheeks, and sometimes under the tongue could be mistaken for tiny cysts.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed)
    • Squamous cell carcinoma: Although rare, any oral lesion, especially those that are new, growing, or do not resolve, should be evaluated for the possibility of oral cancer. Early detection is crucial for treatment outcomes.
    • Lymphoma or other malignancies: Though less common, these can present with oral lesions, including under the tongue, and are critical to diagnose early.
  • Rare diagnoses
    • Dermoid cyst: A rare congenital condition that can present as a cyst under the tongue, containing skin and sometimes other tissue.
    • Thyroglossal duct cyst: Typically found in the midline of the neck, but very rarely, it can present under the tongue if it tracks upwards.
    • Stafne bone cavity: A rare, benign condition where a cavity forms in the jawbone, which might be felt as a soft, cyst-like structure under the tongue if it occurs in the mandible.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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