What imaging modality accurately assesses endometriosis?

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Last updated: February 7, 2025View editorial policy

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From the Guidelines

Transvaginal Ultrasound (TVUS) and MRI Pelvis are the most accurate imaging modalities for assessing endometriosis.

Key Imaging Modalities

  • TVUS: is known to be an accurate study for the evaluation of ovarian endometriomas 1 and has excellent performance for detection of deep endometriosis (DE) when using expanded protocols 1.
  • MRI Pelvis: is an excellent imaging modality for the preoperative diagnosis of endometriosis 1 and has been shown to correspond well with surgical staging systems and histopathologic findings 1.

Important Considerations

  • Expanded TVUS protocols: include evaluation of additional anatomic landmarks and scanning maneuvers, which have shown similar diagnostic performance to pelvic MRI 1.
  • MRI protocols: tailored for detection of DE, with moderate bladder distention and vaginal contrast, can help improve lesion conspicuity involving these structures 1.
  • IV contrast: is helpful in establishing the diagnosis of other pelvic conditions that may present with similar symptoms, such as uterine fibroids or other infectious or inflammatory disorders 1.

Limitations of Other Modalities

  • Transabdominal US: has a limited field of view and may not be able to detect superficial or deep endometriosis lesions 1.
  • FDG-PET/CT: has not been extensively studied for the detection of endometriosis, but may have potential as a diagnostic tool 1.

From the Research

Imaging Modalities for Endometriosis

The following imaging modalities are used to assess endometriosis:

  • Transvaginal ultrasound (TVS)
  • Magnetic resonance imaging (MRI)
  • Three-dimensional sonography (3DUS)

Accuracy of Imaging Modalities

The accuracy of these imaging modalities is as follows:

  • TVS is non-inferior to MRI in the diagnosis and assessment of deep infiltrating endometriosis (DIE) 2
  • TVS can accurately diagnose ovarian endometriomas (OMAs) and deep infiltrating endometriosis (DIE) 2, 3
  • MRI can accurately diagnose deep infiltrating endometriosis and has a wider field of vision 4, 5, 6
  • 3DUS can accurately diagnose deep infiltrating endometriosis in specific locations 3

Recommendations

Based on the evidence, TVS should be considered as the first-line imaging modality in the diagnosis and assessment of endometriosis due to its satisfactory overall diagnostic accuracy, wide availability, and low cost 2 MRI can be used as a complementary imaging modality to TVS, especially in cases where a wider field of vision is needed 5, 6

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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