What are the causes of wheezing (bronoconstriction)?

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Differential Diagnosis for Wheezing

  • Single most likely diagnosis
    • Asthma: This is the most common cause of wheezing, characterized by recurrent episodes of wheezing, coughing, and shortness of breath, often triggered by allergens or irritants.
  • Other Likely diagnoses
    • Chronic Obstructive Pulmonary Disease (COPD): COPD is a progressive lung disease that can cause wheezing, particularly in smokers or those with a history of smoking.
    • Bronchitis: Acute or chronic bronchitis can cause wheezing due to inflammation and irritation of the airways.
    • Pneumonia: Certain types of pneumonia, such as bronchopneumonia, can cause wheezing.
    • Allergic Rhinitis: Postnasal drip and allergic reactions can trigger wheezing in some individuals.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Pulmonary Embolism: Although less common, pulmonary embolism can cause sudden onset of wheezing, particularly if it is large and obstructs major airways.
    • Foreign Body Aspiration: Aspiration of a foreign body can cause sudden onset of wheezing, particularly in children.
    • Anaphylaxis: A severe allergic reaction can cause wheezing, and it is essential to recognize and treat it promptly.
    • Cardiac Conditions (e.g., Heart Failure): In some cases, cardiac conditions can cause wheezing due to pulmonary congestion.
  • Rare diagnoses
    • Cystic Fibrosis: A genetic disorder that can cause chronic respiratory symptoms, including wheezing.
    • Bronchiectasis: A condition characterized by permanent enlargement of parts of the airways, which can cause wheezing.
    • Alpha-1 Antitrypsin Deficiency: A genetic disorder that can cause COPD-like symptoms, including wheezing.
    • Parasitic Infections (e.g., Parasitic pneumonia): Certain parasitic infections can cause wheezing, particularly in immunocompromised individuals.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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