What is the differential diagnosis for a 2-year-old boy with a left eyelid swelling?

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Differential Diagnosis for a 2-year-old boy with a red, swollen eyelid

  • Single most likely diagnosis:
    • Periorbital cellulitis: This is a common condition in children, often caused by bacterial infections such as Staphylococcus aureus or Streptococcus pneumoniae, which can lead to redness, swelling, and warmth of the eyelid.
  • Other Likely diagnoses:
    • Blepharitis: Inflammation of the eyelids, often caused by bacterial or demodex mite infestations, which can cause redness, swelling, and crusting of the eyelids.
    • Conjunctivitis: Infection or inflammation of the conjunctiva, which can cause redness, discharge, and swelling of the eyelid.
    • Hordeolum (stye): A localized infection of the eyelid margin, often caused by Staphylococcus aureus, which can cause a painful, red, and swollen nodule on the eyelid.
  • Do Not Miss diagnoses:
    • Orbital cellulitis: A more severe infection that involves the orbital tissues posterior to the orbital septum, which can cause proptosis, limited eye movement, and vision loss if not promptly treated.
    • Retinoblastoma: A rare but aggressive eye cancer that can cause a red, swollen, and painful eye, although it is less common in this age group.
  • Rare diagnoses:
    • Erythema multiforme: A skin condition characterized by target lesions, which can affect the eyelids and cause redness and swelling.
    • Kawasaki disease: A rare condition that can cause inflammation of the blood vessels, including those in the eyes, leading to redness, swelling, and discharge.
    • Angioedema: A rare condition characterized by rapid swelling of the skin and mucous membranes, which can cause eyelid swelling and redness.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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