From the Research
When taking Eliquis (apixaban) and Prozac (fluoxetine) together, it is crucial to consult with your healthcare provider to determine the appropriate dosing regimen, as Prozac can increase blood levels of Eliquis, potentially increasing bleeding risk. The dosing of Eliquis and Prozac requires careful consideration of individual patient factors, including medical conditions, age, weight, kidney function, and other factors 1. There is a potential interaction between these medications that requires careful management, as Prozac can inhibit certain liver enzymes that metabolize Eliquis, potentially increasing bleeding risk 2. Some key points to consider when taking these medications together include:
- The need for regular monitoring and follow-up appointments to ensure safety and effectiveness
- The potential for increased bleeding risk, which may require adjustments to the Eliquis dose or closer monitoring for signs of bleeding
- The importance of not adjusting medication doses on your own, but rather consulting with your healthcare provider to determine the best course of action
- The fact that apixaban has predictable pharmacokinetics and does not require routine anticoagulation monitoring, but may still require careful management in certain situations 3, 4, 5. In terms of specific dosing recommendations, it is generally recommended to start with a standard dose of Eliquis, such as 5 mg twice daily, and adjust as needed based on individual patient factors and response to treatment 2, 4, 5. However, the exact dosing regimen will depend on a variety of factors, including the patient's medical history, kidney function, and other medications being taken, and should be determined in consultation with a healthcare provider 1.