From the Research
Sermorelin is a well-tolerated analogue of growth hormone-releasing hormone (GHRH) that can be used to diagnose and treat growth hormone deficiency in children and adults, with a typical dosage of 100-300 mcg injected subcutaneously daily.
Uses and Benefits
- Sermorelin stimulates the release of growth hormone from the pituitary gland, which can help improve growth and development in children with idiopathic growth hormone deficiency 1.
- In adults, sermorelin can be used to address growth hormone deficiency, improve body composition, enhance recovery from exercise, and potentially slow certain aspects of aging 2, 3.
- Sermorelin works with the body's natural regulatory system, potentially offering a more physiological approach with fewer side effects than direct growth hormone administration.
Diagnosis and Treatment
- The diagnosis of growth hormone deficiency in adults typically involves stimulation testing, such as the insulin tolerance test or the growth hormone-releasing hormone-arginine test 2, 4.
- Sermorelin can be used as a diagnostic tool to assess growth hormone deficiency, with a peak growth hormone level below a predetermined cutpoint indicating deficiency 1.
- Treatment with sermorelin typically involves daily subcutaneous injections, with regular monitoring of IGF-1 levels and other health parameters to assess efficacy and safety 5, 3.
Safety and Side Effects
- Sermorelin is generally well-tolerated, with mild side effects including injection site reactions, headache, flushing, dizziness, and nausea 1, 3.
- Regular monitoring of IGF-1 levels and other health parameters is recommended during treatment to minimize the risk of adverse effects 2, 5.
- Sermorelin should only be used under medical supervision, as inappropriate use can lead to health complications 1, 3.