Differential Diagnosis for Pain Under the Toe
- Single most likely diagnosis + Morton's neuroma: This condition is characterized by a benign growth of nerve tissue in the ball of the foot, commonly between the third and fourth toes, causing pain, numbness, and tingling. It's a common cause of toe pain and fits the described location.
- Other Likely diagnoses + Ingrown toenail: This occurs when the nail grows into the surrounding skin, causing pain, redness, and swelling. It's a frequent issue that can cause significant pain under the toe. + Bunion: A bony bump at the base of the big toe can cause pain, especially if it rubs against shoes. While it's more about the side of the foot, pressure can radiate under the toe. + Sesamoiditis: Inflammation of the tendons around the sesamoid bones under the first metatarsal bone can cause pain under the big toe.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.) + Osteomyelitis: A bone infection that can occur in any bone but is particularly dangerous in the feet due to the risk of spreading and the challenge of treating infections in this area. + Deep vein thrombosis (DVT): Although more commonly associated with calf pain, DVT can occasionally present with pain in the foot or toes and is a medical emergency due to the risk of pulmonary embolism. + Diabetic foot ulcer: In patients with diabetes, foot ulcers can be a source of significant morbidity and are often found under the toes or on the soles of the feet.
- Rare diagnoses + Gout: While gout typically affects the big toe, it can occasionally cause pain under other toes due to the deposition of urate crystals. + Rheumatoid arthritis: This autoimmune disorder can cause pain and swelling in various joints, including those in the toes. + Peripheral artery disease (PAD): Reduced blood flow to the feet can cause pain, especially under the toes, during walking or at rest.