From the Guidelines
Bisoprolol is commonly sold under the brand name Zebeta in the United States, as well as Concor, Emcor, Monocor, and Soprol in various countries around the world. Bisoprolol is a beta-blocker medication primarily used to treat high blood pressure and heart failure. It works by blocking the action of certain natural chemicals in your body such as epinephrine on the heart and blood vessels, which reduces heart rate, blood pressure, and strain on the heart.
Key Points
- Bisoprolol is typically available in tablet form in strengths of 2.5 mg, 5 mg, and 10 mg.
- The usual starting dose for hypertension is 5 mg once daily, which may be increased to 10 mg if needed, as indicated in the 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults 1.
- For heart failure, treatment usually begins with a lower dose of 1.25 mg and is gradually increased, as recommended in the guidelines for the diagnosis and treatment of chronic heart failure 2.
- Patients should be aware that bisoprolol should not be stopped suddenly as this can worsen certain conditions, and it should be taken at the same time each day for maximum effectiveness.
Important Considerations
- Bisoprolol and metoprolol succinate are preferred in patients with heart failure with reduced ejection fraction (HFrEF), as stated in the 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline 1.
- The use of beta blockers, including bisoprolol, has been shown to reduce mortality and hospitalizations in patients with heart failure, as demonstrated in several studies, including the CAPRICORN study with carvedilol 2.
- Beta blockers, such as bisoprolol, are also effective in secondary prevention after myocardial infarction, imparting a 23% reduction in the odds of death in long-term trials, as reported in the 2017 AHA/ACC clinical performance and quality measures for adults with ST-elevation and non-ST-elevation myocardial infarction 3.
From the Research
Brand Name of Bisoprolol
The provided studies do not mention the brand name of bisoprolol.
- The studies 4, 5, 6, 7, 8 discuss the efficacy and safety of bisoprolol in the treatment of heart failure and arrhythmias, but do not provide information on its brand name.
- Bisoprolol is a generic name, and it may be marketed under different brand names by various pharmaceutical companies.
- However, the studies do not provide this information, and therefore, it is not possible to determine the brand name of bisoprolol based on the provided evidence.