From the FDA Drug Label
The initial dosage of PredniSONE tablets may vary from 5 mg to 60 mg per day, depending on the specific disease entity being treated. IT SHOULD BE EMPHASIZED THAT DOSAGE REQUIREMENTS ARE VARIABLE AND MUST BE INDIVIDUALIZED ON THE BASIS OF THE DISEASE UNDER TREATMENT AND THE RESPONSE OF THE PATIENT After a favorable response is noted, the proper maintenance dosage should be determined by decreasing the initial drug dosage in small increments at appropriate time intervals until the lowest dosage which will maintain an adequate clinical response is reached.
The appropriate Prednisone taper for pleurisy following influenza in a 17-year-old female is not explicitly stated in the drug label.
- The label provides general guidance on dosage and tapering, but does not provide specific recommendations for pleurisy or influenza.
- The dosage requirements are variable and must be individualized based on the disease and patient response.
- A conservative approach would be to consult with a healthcare professional to determine the best course of treatment, including the initial dosage and tapering schedule, for this specific patient 1.
From the Research
Pleurisy Following Influenza
- Pleurisy is inflammation of the pleura, which are the two layers of tissue surrounding the lungs and lining the chest cavity.
- The provided studies do not directly address the appropriate Prednisone taper for pleurisy following influenza in a 17-year-old female.
Relevant Studies
- A study from 2 describes a 17-year-old female who developed granulomatous interstitial nephritis associated with influenza A: H1N1 infection and was treated with tapered prednisone after a starting dose of 2 mg/kg.
- Another study from 3 mentions a 17-year-old female patient with polyserositis, which refers to inflammation of the serous membranes, including the pleura, and was treated with steroids.
- However, these studies do not provide specific guidance on the appropriate Prednisone taper for pleurisy following influenza.
Treatment of Pleurisy
- The treatment of pleurisy typically depends on the underlying cause, and may include antibiotics, antiviral medications, or anti-inflammatory medications such as prednisone.
- The provided studies do not offer a clear recommendation for the appropriate Prednisone taper for pleurisy following influenza in a 17-year-old female, and more research would be needed to determine the best course of treatment.