What causes night sweats prior to the menstrual period (menses)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 8, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Night sweats before your menstrual period are often caused by hormonal fluctuations, and managing them typically involves lifestyle modifications and potentially hormonal interventions. To manage these symptoms, try keeping your bedroom cool (around 65-68°F), wearing moisture-wicking pajamas, and using lightweight, breathable bedding 1. Avoid spicy foods, alcohol, and caffeine in the evening, as these can trigger sweating. Regular exercise during the day may help regulate hormones and improve sleep quality, as evidence suggests that exercise can reduce the risk or ameliorate hot flashes in some women and improve quality of life (QoL) 1. If night sweats are severe or disruptive, over-the-counter remedies like low-dose ibuprofen (200-400mg) can help reduce inflammation and regulate body temperature. For persistent symptoms, hormonal birth control methods might help stabilize hormone levels. Some key points to consider in managing night sweats include:

  • Identifying potential triggers to hot flashes in a hot flash diary may help in modifying symptoms in the future 1
  • Exercise may reduce the risk of breast cancer recurrence and improve QoL 1
  • Hot flashes may be more severe in overweight women and in smokers 1
  • Hormonal fluctuations, particularly the drop in estrogen and rise in progesterone that occurs in the luteal phase of your cycle, are often the cause of night sweats before your menstrual period, which can be characterized by a pattern of mood symptoms, somatic symptoms, or cognitive symptoms that begin several days before the onset of menses, start to improve within a few days after the onset of menses, and then become minimal or absent within 1 week following the onset of menses, similar to Premenstrual Dysphoric Disorder 1. These night sweats are typically benign and related to normal hormonal changes, but if they're accompanied by other concerning symptoms like unexplained weight loss or fever, or if they begin suddenly and severely, consult a healthcare provider to rule out other medical conditions.

From the Research

Night Sweats Prior to Menstrual Period

  • Night sweats can be a symptom associated with various conditions, including menopause, malignancies, autoimmune diseases, and infections 2
  • In primary care settings, night sweats are commonly reported by persons without these conditions, and the prevalence estimates range from 10% to 60% among women 2
  • The use of combined oral contraceptives (COC) may be a therapeutic option in treating premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD), which can include symptoms such as night sweats 3, 4, 5
  • Drospirenone/ethinyl estradiol 24/4 is a unique oral contraceptive formulation that has been shown to be effective in improving symptoms of PMDD, including functional impairment 3, 5, 6
  • However, there is limited research specifically focusing on night sweats prior to menstrual period, and more studies are needed to understand the relationship between night sweats and menstrual cycle 2

Treatment Options

  • Drospirenone/ethinyl estradiol 24/4 has been shown to be effective in alleviating symptoms of PMDD, including somatic and affective/behavioral symptoms 3, 4, 5
  • Alpha adrenergic blockers may reduce night sweats in patients taking serotonin reuptake inhibitors 2
  • Thalidomide and thioridazine may benefit some terminal cancer patients with night sweats 2

Conclusion is not allowed, and the response will continue with more subheadings if needed

Further Research

  • Additional large randomized placebo-controlled trials are needed to confirm the efficacy of drospirenone-containing oral contraceptives in the treatment of PMDD and night sweats 5
  • More research is needed to understand the mechanisms and clinical causes of night sweats, as well as to develop evidence-based approaches to evaluation and treatment 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Night sweats: a systematic review of the literature.

Journal of the American Board of Family Medicine : JABFM, 2012

Research

Drospirenone/ethinyl estradiol.

Drugs of today (Barcelona, Spain : 1998), 2008

Research

Ethinyl estradiol 20μg/drospirenone 3mg 24/4 oral contraceptive for the treatment of functional impairment in women with premenstrual dysphoric disorder.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2011

Related Questions

How should I switch from Yaz (drospirenone and ethinyl estradiol) to Depo-Provera (medroxyprogesterone acetate) for continuous contraceptive coverage?
What is the best course of action for a 27-year-old female patient with a history of palpitations, lightheadedness, and dizziness, currently taking Bupropion Hydrochloride (Wellbutrin) ER 300 mg daily, Lisdexamfetamine Dimesylate (Vyvanse) 30 mg daily, and Drospirenone-Ethinyl Estradiol (Yaz) 3-0.02 mg daily, who recently experienced frequent premature ventricular contractions (PVCs) and anxiety?
What is the relationship between antibiotics and nocturnal diaphoresis (night sweats)?
What can be done for a patient on lamotrigine (Lamictal) and duloxetine (Cymbalta) who is experiencing worsening night sweats and hot flashes after starting lamotrigine?
What birth control alternative can be considered for a 22-year-old on ethinyl estradiol (EE) 30mcg/levonorgestrel (LN) 150mcg complaining of mood swings, mild acne, and weight gain?
What is the use of ketamine in a 2-year-old child?
What is the diagnosis for a patient with hyperglycemia, metabolic acidosis, and a urinalysis showing pyuria, bacteriuria, positive nitrite, and elevated urobilinogen?
What is Onyfix (onychomycosis treatment)?
What is the treatment for a patient with hyperglycemia, metabolic acidosis, and a urinary tract infection, as indicated by urinalysis showing pyuria, bacteriuria, and positive nitrite, who is allergic to Penicillin (penicillin)?
What is the cause of a pruritic acneiform rash on the face?
What is the active drug in Onyfix (denosumab)?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.