What medication is used to facilitate the discharge of cerumen (earwax)?

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Last updated: May 8, 2025View editorial policy

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From the Guidelines

To effectively clean earwax and facilitate discharge, the use of over-the-counter ear drops such as carbamide peroxide (6.5%) is recommended, as evidenced by the clinical practice guideline update on earwax (cerumen impaction) 1. When considering the management of cerumen impaction, it's crucial to understand the role of topical therapy, which can be used alone or in combination with other techniques like irrigation or manual removal. The guideline highlights the existence of topical preparations in three forms: water-based, oil-based, and nonwater, nonoil-based, each with different mechanisms of action 1. Key points to consider when using ear drops for earwax removal include:

  • The application of 5-10 drops of the chosen agent into the affected ear, twice daily for 3-4 days.
  • After instillation, remaining with the head tilted for 5 minutes to allow the solution to soften the wax.
  • Subsequent gentle flushing of the ear with warm water using a bulb syringe to aid in the removal of loosened wax. It's also important to note that alternatives like mineral oil, baby oil, or glycerin drops can be used to soften earwax before irrigation, but their effectiveness and safety profile should be considered in the context of the most recent and highest quality evidence available 1. In cases of severe impaction, ear tubes, perforated eardrum, or ear pain, self-treatment should be avoided, and consultation with a healthcare provider is advised to determine the best course of action.

From the FDA Drug Label

Active ingredients Carbamide peroxide 6.5% Purpose Earwax removal aid The answer is hydrogen peroxide (OTIC), specifically Carbamide peroxide 6.5%, which is used as an Earwax removal aid 2.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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