What is the volume of a bottle of neomycin‑polymyxin B otic solution?

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Last updated: April 23, 2026 • View editorial policy

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Bottle Volume of Neomycin-Polymyxin B Otic Solution

Neomycin-polymyxin B otic solution is supplied in a 10 mL bottle 1.

Product Specifications

The FDA-approved formulation of neomycin and polymyxin B sulfates with hydrocortisone otic solution comes in a white plastic dropper bottle containing 10 mL 1. This is the standard commercial packaging size for this combination otic preparation.

Dosing Context

Understanding the bottle volume is clinically relevant because:

  • Each milliliter contains approximately 10-20 drops depending on solution viscosity 2
  • A 10 mL bottle therefore contains roughly 100-200 drops total
  • Typical dosing is 3-5 drops per application 2
  • This provides sufficient medication for a complete treatment course of acute otitis externa, which typically requires 7-10 days of therapy 3, 4

Storage Requirements

The 10 mL bottle should be stored between 15°C to 25°C (59°F to 77°F), with the cap securely tightened between uses 1.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.