What are the benefits of ferulic acid?

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From the Guidelines

Ferulic acid is a potent antioxidant that offers several benefits, including protecting against cell damage, reducing inflammation, and improving skin health 1. The benefits of ferulic acid can be attributed to its ability to inhibit the formation of advanced glycation end-products (AGEs), which are harmful compounds that can accumulate in the body and contribute to various diseases.

Key Benefits of Ferulic Acid

  • Anti-glycative properties: Ferulic acid has been shown to exhibit anti-glycative properties, which can help reduce the formation of AGEs in the body 1.
  • Antioxidant activity: Ferulic acid has potent antioxidant activity, which can help protect against cell damage and reduce inflammation 1.
  • Skin health benefits: Ferulic acid may also have benefits for skin health, including improving skin elasticity and reducing the appearance of fine lines and wrinkles.

Recommended Intake and Precautions

It is recommended to consume 50-500 mg of ferulic acid per day, either through dietary sources such as fermented foods, or as a supplement 1. However, it is essential to consult with a healthcare professional before taking ferulic acid supplements, especially if you are taking medications such as blood thinners, as it may interact with them. Additionally, ferulic acid may be combined with other antioxidants like vitamin C and vitamin E to enhance its benefits. Pregnant or breastfeeding women should exercise caution and consult their healthcare provider before using ferulic acid supplements.

Food Sources and Culinary Practices

Ferulic acid can be found in various food sources, including fermented foods, and can also be added to foods during cooking to reduce AGE formation 1. Culinary practices such as using lower cooking temperatures, steaming, stewing, and poaching, and adding acids like vinegar or lemon juice to food can also help reduce AGE levels.

From the Research

Benefits of Ferulic Acid

The benefits of ferulic acid can be summarized as follows:

  • Antioxidant properties: Ferulic acid has been shown to scavenge free radicals and enhance the cell stress response through the up-regulation of cytoprotective systems 2, 3, 4, 5
  • Potential treatment for various diseases: Ferulic acid has been proposed as a potential treatment for many disorders including Alzheimer's disease, cancer, cardiovascular diseases, diabetes mellitus, and skin disease 2, 6, 4
  • Anti-inflammatory effects: Ferulic acid has been shown to inhibit the expression and/or activity of cytotoxic enzymes, including inducible nitric oxide synthase, caspases, and cyclooxygenase-2 2, 4
  • Photoprotective effects: Ferulic acid has been shown to protect skin from UV radiation and prevent photoaging 3, 5
  • Wound healing: Ferulic acid has been shown to accelerate wound healing and enhance angiogenesis 5

Potential Applications

The potential applications of ferulic acid include:

  • Pharmaceutical industry: Ferulic acid has been proposed as a potential treatment for various diseases 2, 6, 4
  • Food industry: Ferulic acid has been shown to inhibit lipid peroxidation and prevent oxidative spoilage of foods 3
  • Cosmetics industry: Ferulic acid has been widely used in skin care formulations as a photoprotective agent, delayer of skin photoaging processes, and brightening component 5

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Ferulic acid: pharmacological and toxicological aspects.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014

Research

Antioxidant potential of ferulic acid.

Free radical biology & medicine, 1992

Research

Antioxidant Properties of Ferulic Acid and Its Possible Application.

Skin pharmacology and physiology, 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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