Differential Diagnosis for 23-year-old Female with Pain along the Base of the 5th Metatarsal
- Single most likely diagnosis
- Peroneal Tendinosis or Peroneus Brevis Tendinitis: This condition is common in runners, especially after a period of increased activity. The pain and bruising along the base of the 5th metatarsal are consistent with this diagnosis, as the peroneal tendons run along this area.
- Other Likely diagnoses
- Cuboid Syndrome: This condition involves inflammation of the cuboid bone and surrounding tissues, which can cause pain along the base of the 5th metatarsal. It is often seen in runners and can be caused by overuse or poor foot mechanics.
- 5th Metatarsal Stress Reaction: Although the x-ray was negative for a fracture, a stress reaction (early stage of a stress fracture) is still possible. This condition can cause pain and bruising in the affected area.
- Peroneal Tenosynovitis: Inflammation of the tendon sheath surrounding the peroneal tendons can cause pain and swelling along the base of the 5th metatarsal.
- Do Not Miss diagnoses
- Compartment Syndrome: This is a serious condition that can cause pain, swelling, and bruising in the foot and ankle. It is often seen in athletes and can be caused by increased pressure within the muscle compartments.
- Deep Vein Thrombosis (DVT): Although less likely, DVT can cause pain and swelling in the foot and ankle, and it is essential to consider this diagnosis, especially if the patient has a history of blood clots or is taking oral contraceptives.
- Rare diagnoses
- Tumor or Cyst: A tumor or cyst in the foot can cause pain and bruising, although this is a rare possibility.
- Infection: An infection, such as osteomyelitis or septic arthritis, can cause pain, swelling, and bruising in the foot and ankle, although this is unlikely without other symptoms such as fever or redness.