From the Guidelines
Vitamin E for relieving hot flashes in menopause is recommended at a dose of 800 IU/day, but with caution due to potential increased risk of all-cause mortality at doses above 400 IU/day 1.
- The evidence suggests that high-dose vitamin E has shown limited efficacy in reducing hot flashes in menopausal women 1.
- However, it is crucial to note that supplemental vitamin E at doses above 400 IU/day has been linked to an increase in all-cause mortality 1, emphasizing the need for careful consideration and consultation with a healthcare provider before initiating treatment.
- As such, while 800 IU/day of vitamin E may be considered for relieving hot flashes, it is essential to weigh the potential benefits against the potential risks and to explore other treatment options under the guidance of a healthcare professional.
From the Research
Recommended Dose of Vitamin E for Relieving Hot Flashes in Menopause
- The recommended dose of vitamin E for relieving hot flashes in menopause is 800 IU/d, as suggested by a study published in the Mayo Clinic proceedings 2.
- Another study published in the Gynecologic and obstetric investigation journal found that 400 IU of vitamin E daily can significantly reduce the severity and frequency of hot flashes in menopausal women 3.
- However, it is essential to note that the evidence for the efficacy of vitamin E in relieving hot flashes is not consistent across all studies, and some studies have found conflicting results 4.
Comparison with Other Treatments
- Estrogen replacement therapy is considered the most effective treatment for hot flashes, with a success rate of 80-90% 2.
- Other treatments, such as antidepressants and progestational agents, may also be effective in relieving hot flashes 2, 5.
- Botanical and dietary supplements, such as black cohosh and soy products, have also been studied for their potential to relieve hot flashes, but the evidence is limited and inconsistent 6, 4.
Important Considerations
- Women should consult with their healthcare providers before starting any new supplements or treatments for hot flashes.
- The long-term safety and efficacy of vitamin E and other alternative therapies for hot flashes are not well established, and more research is needed to fully understand their effects 4.