From the Guidelines
Calmoseptine ointment can be used as a supportive treatment for atopic dermatitis, particularly when skin is irritated or has moisture-associated damage, but it should not replace primary treatments such as topical corticosteroids, calcineurin inhibitors, or moisturizers 1. When considering the use of Calmoseptine for atopic dermatitis, it is essential to prioritize the management of the condition based on its severity and impact on the patient's quality of life.
Key Considerations
- For most people with atopic dermatitis, emollients and prescription topical therapies are sufficient to achieve control 1.
- Calmoseptine contains zinc oxide (20%) and menthol (0.44%), which provide barrier protection, mild antiseptic properties, and soothing relief from itching and discomfort.
- The decision to initiate more advanced therapies, such as phototherapy or systemic therapies, should be made using shared decision-making between patients and clinicians, taking into account the severity of AD, its impact on the patient, and the efficacy, safety, and accessibility of the available interventions 1.
Recommendations
- Apply a thin layer of Calmoseptine to clean, dry affected areas 2-3 times daily or as needed to create a protective barrier.
- Use Calmoseptine as an adjunct therapy for specific irritated areas rather than as a primary treatment for widespread atopic dermatitis.
- Monitor for temporary stinging upon application due to the menthol content, and be aware that the pink color can stain clothing.
- If irritation worsens or symptoms don't improve after several days of use, discontinue and consult a healthcare provider.
Prioritizing Morbidity, Mortality, and Quality of Life
The management of atopic dermatitis should prioritize reducing morbidity, mortality, and improving quality of life.
- The use of Calmoseptine as a supportive treatment can help alleviate symptoms and improve quality of life for patients with atopic dermatitis.
- However, it is crucial to use Calmoseptine in conjunction with primary treatments and under the guidance of a healthcare provider to ensure optimal management of the condition.
From the FDA Drug Label
Temporarily protects irritated areas. For the temporary relief of: local itching and discomfort in the perianal area pain or burning skin irritations The FDA drug label does not answer the question.
From the Research
Calmoseptine and Atopic Dermatitis
- There is no direct mention of Calmoseptine in the provided studies 2, 3, 4, 5, 6.
- The studies discuss various treatments for atopic dermatitis, including topical corticosteroids, topical calcineurin inhibitors, moisturizers, and phototherapy 2, 3, 4, 5, 6.
- Topical calcineurin inhibitors, such as tacrolimus and pimecrolimus, are mentioned as alternative treatments to topical corticosteroids for atopic dermatitis 3, 4, 6.
- Moisturizers and emollients are recommended for improving skin barrier function and reducing inflammation in atopic dermatitis 2, 3, 5, 6.
- There is no evidence to suggest that Calmoseptine is used in the treatment of atopic dermatitis based on the provided studies.