RMR is Not the Same as BMR
RMR (resting metabolic rate) is approximately 10% higher than BMR (basal metabolic rate), though the terms are often used interchangeably in clinical practice. 1, 2
Key Differences in Measurement Conditions
BMR Measurement Requirements
BMR represents the minimal energy expenditure compatible with life and requires strictly controlled laboratory conditions 2:
- Measured in a recumbent position
- Thermo-neutral environment
- After 12-18 hours of fasting
- Immediately upon awakening before any daily activities begin
- No physical activity
RMR Measurement Requirements
RMR is measured under less stringent conditions 1:
- Can be measured at any resting state throughout the day
- Requires only 4 hours of fasting (not 12-18 hours)
- Patient should be seated and rested for 10 minutes prior to testing
- No intense physical activity for 4 hours before measurement
- No tobacco use for 1 hour before testing
The 10% Difference in Clinical Practice
The consistent finding across multiple guidelines is that RMR measures approximately 10% higher than BMR 1, 2. This difference exists because:
- RMR includes slightly more metabolic activity than the absolute basal state
- Measurements occur under less controlled conditions
- Some residual effects of recent food intake or activity may persist
Clinical Application
In practical metabolic calculations, this 10% difference is actually built into standard formulas. When calculating total energy expenditure (TEE):
- Using BMR: TEE = BMR × physical activity level (PAL) × 1.1 (for thermogenesis)
- Using RMR: TEE = RMR × PAL (the 10% for thermogenesis is already included in the RMR value) 1
For sedentary individuals: TEE = RMR × 1.2 1
For active individuals: TEE = RMR × 1.6 1
Important Clinical Caveats
While the terms are often used interchangeably in clinical settings, understanding the distinction matters when:
Comparing measured values to predicted equations - Most prediction equations (Harris-Benedict, Mifflin-St Jeor) estimate RMR, not true BMR 3, 4
Interpreting indirect calorimetry results - Office-based measurements typically yield RMR/REE values, which are 10% above basal energy expenditure 1
Calculating energy prescriptions - The 10% difference must be accounted for to avoid overfeeding or underfeeding 1
The pediatric guidelines 2 emphasize that REE (resting energy expenditure) does not differ by more than 10% from BMR, confirming this relationship holds across age groups.