From the Guidelines
Ryaltris can potentially cause loss of taste or altered taste sensation, though this is not among its most common side effects. This medication, used to treat seasonal allergic rhinitis, contains a corticosteroid and an antihistamine that can affect taste receptors when the spray drips down the back of the throat (post-nasal drip) 1. The exact formulation of Ryaltris, which includes olopatadine and mometasone furoate, may contribute to taste disturbances, as both components have been associated with bitter taste in other studies 1.
Key Considerations
- The medication's potential to cause taste disturbances is likely due to the post-nasal drip effect, where the spray reaches the taste buds in the back of the throat.
- Proper administration technique can help minimize the amount of medication that reaches the taste buds, such as tilting the head slightly forward when spraying, aiming away from the nasal septum, and avoiding strong sniffing after application.
- If taste changes persist or become bothersome, consulting a healthcare provider may lead to recommendations for adjusting the technique or considering alternative treatments.
Evidence-Based Recommendations
Based on the most recent and highest quality study available 1, it is essential to prioritize the patient's quality of life and minimize potential side effects. Therefore, healthcare providers should educate patients on proper administration techniques and monitor them for any adverse effects, including taste disturbances. By doing so, patients can benefit from the medication's efficacy in treating seasonal allergic rhinitis while minimizing its potential impact on their quality of life.
From the Research
Ryaltris and Loss of Taste
- Ryaltris is a combination of azelastine and fluticasone propionate, and there is limited information directly linking it to loss of taste.
- However, studies on azelastine, a component of Ryaltris, report that bitter taste is a common side effect associated with its use 2, 3.
- The bitter taste is often attributed to incorrect dosing technique and can be mitigated by following the recommended administration technique 2, 3.
- There is no direct evidence in the provided studies to suggest that Ryaltris or its components cause loss of taste, but rather a bitter taste which is a distinct symptom.
- A study on COVID-19 patients found that fluticasone nasal spray and triamcinolone paste improved smell and taste disorders, but this is not directly related to Ryaltris or its potential to cause loss of taste 4.
- Another study examined the gene expression profiles in response to azelastine and fluticasone propionate combination or monotherapy, but did not investigate the effect on taste 5.