What is the cause of a knot above the ear?

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Last updated: May 9, 2025View editorial policy

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Differential Diagnosis for a Knot Above the Ear

  • Single most likely diagnosis
    • Epidermal cyst (sebaceous cyst): A common, benign cyst that can form on the skin, including the scalp, and may present as a knot or lump.
  • Other Likely diagnoses
    • Folliculitis: An inflammation of the hair follicles, which can cause redness, swelling, and knots or bumps on the scalp.
    • Furuncle (boil) or carbuncle: A bacterial infection of the skin and subcutaneous tissue, which can cause a painful knot or lump.
    • Abscess: A collection of pus that can form on the skin, including the scalp, and may present as a painful knot or lump.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Meningioma: A rare, usually benign tumor that arises from the meninges, which can cause a lump or knot on the scalp, and may be life-threatening if not diagnosed and treated.
    • Osteoma: A rare, benign tumor of the bone, which can cause a hard, fixed knot or lump on the scalp.
    • Metastatic tumor: A rare, but potentially life-threatening condition, where cancer from another part of the body spreads to the scalp, causing a knot or lump.
  • Rare diagnoses
    • Dermatofibroma: A rare, benign skin growth that can cause a firm, knot-like lump on the scalp.
    • Pilomatrixoma: A rare, benign tumor of the hair follicle, which can cause a firm, knot-like lump on the scalp.
    • Neurofibroma: A rare, benign tumor of the nerve tissue, which can cause a knot or lump on the scalp, and may be associated with neurofibromatosis type 1.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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