From the Guidelines

The effective oral dose of hyaluronic acid (HA) for treating osteoarthritis (OA) is typically in the range of 50-200 mg per day 1.

Some studies suggest that higher doses may be more effective, but due to limited strong evidence, it is recommended to start with a lower dose of 50 mg per day and gradually increase as needed and under medical supervision 1.
Treatment duration can vary, but typically ranges from 2-6 months.
It is essential to consult with a healthcare professional before starting any new supplement regimen, especially for individuals with underlying medical conditions or taking other medications.
The use of hyaluronic acid and other symptomatic slow-acting drugs for OA (SYSADOA) may possess structure modification properties, but more studies are required to confirm this 1.
Hyaluronic acid is probably effective in knee OA, but the size effect is relatively small, and suitable patients are not well defined 1.
The introduction of hyaluronic acid has been viewed as an advance in the management of knee OA, with its role in pain reduction, functional improvement, and disease modification in knee OA being assessed 1.

From the Research

The effective oral dose of hyaluronic acid (HA) for treating osteoarthritis (OA) is not consistently defined across studies, but some research provides insight into dosages that have shown promise.
A study published in 2012 2 investigated the efficacy of oral HA administration for OA in knee joints, where subjects in the HA group were given 200 mg of HA once a day every day for 12 months.
Another study from 2008 3 examined the effect of dietary supplementation with a natural extract of chicken combs with a high content of hyaluronic acid (60%) at a dose of 80 mg/day for 8 weeks.
A 2015 study 4 used an oral preparation containing hyaluronic acid (Oralvisc®) but does not specify the exact dosage of hyaluronic acid in the preparation.

The 2012 study 2 found that oral administration of HA may improve the symptoms of knee OA in patients aged 70 years or younger when combined with quadriceps strengthening exercise.
The 2008 pilot study 3 showed that daily supplementation with oral hyaluronic acid from a natural extract of chicken combs was useful to enhance several markers of quality of life in adults with osteoarthritis of the knee.
The 2015 study 4 found statistically significant improvements in pain and function, as well as decreases in inflammatory cytokines, leptin, and bradykinin, in the oral hyaluronic acid preparation group.

While these studies suggest potential benefits of oral HA supplementation for OA, the optimal dosage and treatment duration remain to be fully determined.
Further research is needed to confirm these findings and establish a standardized effective oral dose of hyaluronic acid for treating osteoarthritis.