From the Research
Hyaluronic Acid and Sodium Hyaluronate Relationship
- The relationship between hyaluronic acid and sodium hyaluronate is crucial in determining the equivalent volume of hyaluronic acid for a given amount of sodium hyaluronate powder.
- However, the provided studies do not directly address the conversion of sodium hyaluronate powder to hyaluronic acid volume 1, 2, 3, 4, 5.
Sodium Hyaluronate Properties
- Sodium hyaluronate is a polymer of disaccharides, composed of d-glucuronic acid and d-N-acetylglucosamine, linked via alternating β-1,4 and β-1,3 glycosidic bonds 1.
- The molecular weight of sodium hyaluronate can affect its rheological properties, such as bulk viscosity 4, 5.
Rheological Properties
- Solutions containing high molecular weight hyaluronate at concentrations around 10 mg/ml exhibit interesting rheological properties due to formation of a highly entangled network of flexible polysaccharide molecules 4.
- The bulk viscosity of hyaluronate solutions is strongly dependent both on concentration and molecular weight 4.