From the FDA Drug Label
For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested: ... children over 6 years, 50 to 100 mg daily in divided doses. For use in the management of pruritus due to allergic conditions ... children over 6 years, 50 to 100 mg daily in divided doses. As a sedative when used as a premedication and following general anesthesia: ... 0. 6 mg/kg of body weight in children.
The recommended dosage of hydroxyzine for a 12-year-old child is 50 to 100 mg daily in divided doses for anxiety and pruritus, or 0.6 mg/kg of body weight when used as a sedative 1.
From the Research
Hydroxyzine can be used for 12-year-old children under proper medical supervision, with a recommended dosage of 0.5-1 mg/kg per dose given every 6 hours as needed, and a maximum daily dose of 50-100 mg divided throughout the day. The medication is an antihistamine that may be prescribed for anxiety, itching from allergic reactions, or as a sedative before medical procedures. Common side effects include drowsiness, dry mouth, and dizziness, which parents should monitor 2.
Key Considerations
- Hydroxyzine works by blocking histamine receptors and has some effects on serotonin pathways in the brain, helping to reduce anxiety and itching sensations.
- It's essential that hydroxyzine only be given to a 12-year-old with a doctor's prescription and specific dosing instructions, as individual factors like weight, medical history, and concurrent medications need to be considered.
- Parents should ensure their child takes the medication exactly as prescribed and report any concerning side effects to their healthcare provider immediately.
Evidence Summary
The most recent and highest quality study, a 3-level network meta-analysis published in 2021, found that all medications, including SSRIs and SNRIs, were effective for multiple symptom domains, and in patients from all included diagnostic categories, with minimal differences between medications concerning efficacy and acceptability 2. Although this study did not specifically focus on hydroxyzine, it provides valuable insights into the treatment of anxiety and other related disorders, which are relevant to the use of hydroxyzine in 12-year-old children.
Important Notes
- The use of hydroxyzine in children should be carefully monitored due to potential side effects and interactions with other medications.
- Alternative treatments, such as behavioral therapy or other medications, may be considered depending on the individual child's needs and medical history.
- Regular follow-up with a healthcare provider is crucial to ensure the safe and effective use of hydroxyzine in 12-year-old children.